Gene interactions and pathways from curated databases and text-mining

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BAX — IRF3

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Sharif-Askari et al., Virology 2007 (Rhabdoviridae Infections) : Moreover, Bax but not Bak pro-apoptotic protein was required for IRF-3 phosphorylation and activation, further substantiating a role for the intrinsic mitochondrial pathway in the innate immune response
Chattopadhyay et al., EMBO J 2010 : Viral apoptosis is induced by IRF-3 mediated activation of Bax