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Maquarre et al., Leukemia 2005
(Leukemia, Promyelocytic, Acute) :
We show that A3D8 induces activation of both initiator caspase-8 and -9 and effector caspase-3 and -7 but only inhibition of caspase-3/7 and caspase-8 reduces A3D8 induced apoptosis
Qian et al., Cancer Biol Ther 2012
(Leukemia, Myeloid, Acute) :
The mechanism of A3D8 induced caspase-8 activation was studied in APL NB4 cells