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CDH1 — MYC

Text-mined interactions from Literome

Liu et al., Am J Physiol Cell Physiol 2009 : The current study was performed to determine whether polyamines induce E-cadherin expression through the transcription factor c-Myc and whether polyamine regulated E-cadherin plays a role in maintenance of the epithelial barrier integrity ... Experiments using different E-cadherin promoter mutants revealed that induction of E-cadherin transcription by c-Myc was mediated through the E-Pal box located at the proximal region of the E-cadherin promoter
Dai et al., Xi Bao Yu Fen Zi Mian Yi Xue Za Zhi 2012 (Carcinoma, Squamous Cell...) : E-cadherin promoter activity in response to Myc-Twist1 overexpression was measured by the dual luciferase reporter assay system
Liu et al., Cell Biol Int 2013 : c-Myc suppressed E-cadherin through miR-9 at the post-transcriptional level ... E-cadherin expression is repressed by MYC through a post-transcriptional mechanism, but the exact mechanism remains elusive ... Overexpressed c-Myc led to an EMT-like conversion in the T-REx-293 cells and resulted in a significant decrease in E-cadherin and an increase in Vimentin ... Thus c-Myc represses E-cadherin at the post-transcriptional level through miR-9
Batsché et al., Mol Cell Biol 1998 : RB and c-Myc activate expression of the E-cadherin gene in epithelial cells through interaction with transcription factor AP-2 ... Here we show that both RB and c-Myc specifically activate transcription of the E-cadherin promoter in epithelial cells but not in NIH 3T3 mesenchymal cells