Ryder et al., J Biol Chem 2000
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Stimulation of MSK1 in contracting skeletal muscle required the activation of both ERK and p38 ( MAPK )
Markou et al., Biochem J 2002
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Phosphorylation and activation of MSK1 was completely inhibited by either PD98059 ( ERK1/2 pathway inhibitor ) or SB203580 ( p38 MAPK inhibitor ) alone
El Mchichi et al., Cell Death Differ 2007
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Inhibition of p38 activity using either pharmacological inhibitors or dominant negative mutant forms of p38 blocked Mn ( 2+ ) -mediated phosphorylation of MSK1 and blocked subsequent caspase-8 activation
Deak et al., EMBO J 1998
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Mitogen- and stress activated protein kinase-1 ( MSK1 ) is directly activated by MAPK and SAPK2/p38 , and may mediate activation of CREB