Gene interactions and pathways from curated databases and text-mining

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AKT1 — CYP19A1

Text-mined interactions from Literome

Zeleznik et al., Endocrinology 2003 : The expression of the constitutively active PKB in combination with the constitutively active LH receptor D578H, the constitutively active G ( s ) alpha Q227L, or 8-bromo-cAMP led to an induction of aromatase as well as LH receptor mRNA comparable to that seen in cells stimulated with FSH alone
Su et al., J Steroid Biochem Mol Biol 2011 (Breast Neoplasms) : Our study reveals that PI3K/Akt and MAPK inhibitors suppressed aromatase activity in MCF-7aro cells ... However, PI3K/Akt pathway inhibitors stimulated aromatase activity in T47Daro cells