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CRK — MMP9
Text-mined interactions from Literome
Xue et al., Arthritis Rheum 2007
(Arthritis, Rheumatoid...) :
Furthermore, APC directly suppressed the production of tumor necrosis factor (TNF) and the activation of NF-kappaB and MAP kinase p38, and inhibitors of NF-kappaB or p38 reduced the production of MMP-9, suggesting that APC
inhibits MMP-9 by blocking TNF, NF-kappaB, and
p38
Mühlen et al., Virus Res 2009
(Carcinoma...) :
AP-1 and ERK1 but not
p38 nor JNK is
required for CRPV early protein 2-dependent
MMP-9 promoter activation in rabbit epithelial cells
Lee et al., Inflammation 2011
(Breast Neoplasms...) :
These signaling molecules and additional
p38 ( MAPK ) were also
involved in macrophage induced
MMP-9 expression
Turner et al., Matrix Biol 2010
:
Pharmacological inhibitors of p38-a/ß ( SB203580 ) or
p38-a/ß/?/d ( BIRB-0796 ) reduced MMP-3 and ADAMTS1 mRNA expression, but neither inhibitor
affected MMP-9 levels
Ling et al., Br J Pharmacol 2010
(Breast Neoplasms...) :
By using specific inhibitors, it was demonstrated that ERK and NF-?B signalling, but not JNK and
p38 signalling, were
involved in PMA stimulated
MMP-9 activation
Deraz et al., PloS one 2011
(Carcinoma, Squamous Cell...) :
Interestingly,
MMP-10 overexpression
induced the decreased
p38 activity and MMP-10 knockdown induced the increased p38 activity
Heijink et al., Thorax 2013
(Pulmonary Disease, Chronic Obstructive) :
Exogenously added WNT-4 significantly increased CXCL8/IL-8, IL-6, CCL5/RANTES, CCL2/MCP-1 and vascular endothelial growth factor ( VEGF ) secretion in 16HBE, but did not affect the canonical WNT target genes MMP-2,
MMP-9 , fibronectin, ß-catenin, Dickkopf and axin-2, and induced
activation of the non-canonical signalling molecule
p38