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IFI27 — MAPK1
Text-mined interactions from Literome
Lenferink et al., Cancer Res 2001
(Breast Neoplasms...) :
Consequently, both
MAPK dependent transcription of cyclin D1 and phosphorylation of the cyclin dependent kinase (Cdk) inhibitor
p27 were inhibited
Baselga et al., J Clin Oncol 2005
(Bone Neoplasms...) :
while phosphorylation of
mitogen activated protein kinase was inhibited in both tissues, gefitinib treatment
induced p27 and a decrease in Ki67 in skin but not in tumors
Joshi et al., Oncogene 2007
(Adrenal Gland Neoplasms...) :
RET2A mediated regulation of p18 and
p27 , but not of cyclins D1 and D2,
requires functional
mitogen activated protein kinase signaling
Pang et al., J Cell Physiol 2008
:
Our study demonstrated that both the functional DRE and the phosphorylation of
p38MAPK are
essential for the induction of p21 and
p27 , resulting in the antiproliferative action of 3MC in HUVECs
Benson et al., Blood 2009
(MAP Kinase Signaling System) :
The effect results at least in part via enhanced
MAPK mediated modulation of
p27 and CDK4
Pillai et al., Int J Biochem Cell Biol 2011
(Anoxia...) :
p27 induction in hypoxic cardiac fibroblasts may
involve direct transcriptional regulation, independent of p38
MAPK , and post-translational regulation via p38 MAPK dependent suppression of its degradation by Skp2