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NGF — NTRK2
Pathways - manually collected, often from reviews:
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
-
STRING interaction:
NTRK2
—
NGF
(interaction, mapped from bind reactome)
-
STRING interaction:
NGF
—
NTRK2
(interaction, mapped from bind reactome)
Text-mined interactions from Literome
Li et al., Blood 2009
(Cell Transformation, Neoplastic...) :
Activation of TRKA or
TRKB by
NGF and BDNF, respectively, efficiently rescued murine myeloid cells from irradiation induced apoptosis
Moubarak et al., J Neurosci 2010
:
Finally, we demonstrate that FLIP-L interacts with TrkA, and not with p75 ( NTR ), in an
NGF dependent manner, and endogenous FLIP-L interacts with
TrkB in whole-brain lysates from embryonic day 15 mice embryos
Sato et al., Cell Mol Neurobiol 2011
:
Interestingly, the GFP labeled neurons grew dendrites and activated the
TrkA/TrkB receptors in
response to
NGF , but not BDNF
Xie et al., Neuroreport 1997
(Leukemia) :
Furthermore, while no expression of
trkB and trkC was detected, constitutive expression of
nerve growth factor (NGF) , neurotrophin-3 and neurotrophin-4/5 could be
detected in leukemia cells
Bogenmann et al., Oncogene 1998
(Neuroblastoma) :
Functional
nerve growth factor (NGF) responsiveness was investigated in human neuroblastoma ( NB ) cell lines in vitro and retinoic acid ( RA ) was found to transcriptionally
enhance expression of the trkA, but not the
trkB gene in GOTO cells, while the reverse was found in HTLA230 NB cells