Liu et al., Endocrinology 2001
:
Induction of iNOS expression by PIC and IFN-gamma requires nuclear factor-kappaB activation, as suggested by transfection experiments with iNOS promoter-luciferase reporter constructs into primary beta-cells ... The transcription factor nuclear factor-kappaB is required for PIC induced iNOS expression
Jin et al., Pharmacol Res 2006
:
PIC also attenuated the expression of inducible NO synthase (iNOS) and cyclooxygenase (COX)-2 mRNA and protein levels