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EIF2AK2 — GRAP2

Text-mined interactions from Literome

Pavio et al., J Virol 2002 : Alpha interferon ( IFN-alpha ) treatment or overexpression of the double stranded RNA activated protein kinase ( PKR ) significantly increased the stability of E2-p38 , consistent with a previous report ( D. R. Taylor, S. T. Shi, P. R. Romano, G. N. Barber, and M. M. Lai, Science 285 : 107-110, 1999 ) that E2 interacts with PKR and inhibits its kinase activity
Russell et al., Exp Cell Res 2009 (Atrophy...) : Activation of PKR also led to activation of p38MAPK ( mitogen activated protein kinase ), leading to ROS ( reactive oxygen species ) formation, since this was attenuated by the specific p38MAPK inhibitor SB203580
Li et al., FEBS Lett 2012 : PKR mediated activation of JNK1 and p38 MAPK is required for both ATX and LPA ( 3 ) up-regulation