Grill et al., Blood 2002
(MAP Kinase Signaling System) :
Rac-1 was also activated by colony stimulating factor-1 (CSF-1) , Steel locus factor ( SLF ), granulocyte-macrophage colony stimulating factor ( GM-CSF ), and IL-5 or by cross linking the B-lymphocyte receptor for antigen (BCR)
Kim et al., BMB Rep 2010
:
On the other hand, GCs potently suppress osteoclast resorptive activity by disrupting its cytoskeleton based on the inhibition of RhoA, Rac and Vav3 in response to macrophage colony stimulating factor