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MS — TNF
Text-mined interactions from Literome
Bitsch et al., Glia 2000
(Demyelinating Diseases...) :
The precise
role of
tumour necrosis factor alpha (TNFalpha) in
multiple sclerosis (MS) is still controversial
Zai-Xing et al., J Clin Lab Anal 2008
(Arthritis, Rheumatoid...) :
It has recently been reported that
tumor necrosis factor (TNF) related apoptosis inducing ligand ( TRAIL )
plays various roles in such autoimmune diseases as diabetes,
multiple sclerosis (MS) , and systemic lupus erythematosus ( SLE )
Zipp et al., Ann Neurol 1995
(Disease Susceptibility...) :
Genetic control of
multiple sclerosis :
increased production of lymphotoxin and
tumor necrosis factor-alpha by HLA-DR2+ T cells
Claudio et al., Lab Invest 1994
:
These results demonstrate that proinflammatory
effects of IL-1 beta and
TNF-alpha in the BRB initiate many of the changes associated with inflammation of the CNS vasculature, such as those induced during experimental autoimmune encephalitis and
multiple sclerosis
Rieckmann et al., J Neuroimmunol 1996
(Autoimmune Diseases...) :
Increasing doses of PTX significantly reduced
TNF-alpha and IL-12 mRNA expression of blood mononuclear cells, but
increased IL-4 and IL-10 expression in eight patients with relapsing remitting
multiple sclerosis
Salmaggi et al., J Neurol 1997
(Multiple Sclerosis) :
The decrease in
TNF-alpha levels and the increase in `` suppressor-inducer '' lymphocytes could
reduce chronic inflammation in
multiple sclerosis , and paralleled an overall favourable clinical response to azathioprine treatment in our patients