Gene interactions and pathways from curated databases and text-mining

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MAP3K13 — POLDIP2

Text-mined interactions from Literome

Bloem et al., J Mol Cell Cardiol 2001 (Cardiomegaly...) : When expressed in cardiac myocytes, MLK7 activated SAPK/JNK1, and ERK and p38 to a lesser extent
Schoorlemmer et al., J Biol Chem 2002 (MAP Kinase Signaling System) : Mixed lineage kinase 3 (MLK3) and IB2 synergistically activate p38delta but not the MAPKs JNK-1 and p38alpha
Abi Saab et al., Oncogenesis 2012 : However, here we report that MLK4ß , unlike the other MLKs, negatively regulates the activities of the MAPKs, p38 , c-Jun N-terminal kinase and extracellular signal regulated kinase, and the MAP2Ks, MEK3 and 6