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SMN1 — TGFB2
Text-mined interactions from Literome
Osaki et al., Int J Exp Pathol 2001
(Pulmonary Fibrosis) :
When pulmonary fibroblasts were separated from saline injected rats ( N-Fib ) and cultivated for 7 days in the presence of 5 mg/mL PLM, alpha-SMA protein was weakly expressed, while the majority of pulmonary fibroblasts separated from PLM injected rats ( P-Fib ) became positive for alpha-SMA in 7-day cultivation and the expression of
alpha-SMA in P-Fib was strongly increased by cultivation in the
presence of PLM and
transforming growth factor-beta ( TGF-beta ), but not basic fibroblast growth factor (bFGF) or platelet derived growth factor ( PDGF ), although the cell proliferation was most strongly enhanced by bFGF and only slightly by PLM and TGF-beta
Batra et al., Clin Exp Allergy 2004
(Asthma) :
TGF-beta1,
TGF-beta2 and IL-4 significantly
increased alpha-SMA in fibroblasts, but only IL-4 caused corresponding increases in collagen III synthesis
Izumi et al., Invest Ophthalmol Vis Sci 2006
:
TGF-beta2 but not IGF-I potently
stimulated alpha-SMA mRNA expression
Gamulescu et al., Exp Eye Res 2006
:
TGFbeta2 induced a significant increase of
alpha-SMA expression in a dose dependent manner
Sandbo et al., Cardiovasc Res 2007
(Shock, Septic) :
We show that
SMA expression in VSMC,
induced by endothelin-1 (ET1) or
transforming growth factor-beta ( TGF-beta ), is potently inhibited by a LPS
Gotoh et al., Invest Ophthalmol Vis Sci 2007
(Cataract...) :
TGF-beta2 increased the production of collagen type I, fibronectin, and
alpha-SMA
Kurosaka et al., Invest Ophthalmol Vis Sci 1995
:
TGF-beta 2 increased collagen gel contraction and
alpha-SMA expression in bovine LECs, whereas bFGF decreased these parameters
Kurosaka et al., Curr Eye Res 1996
:
To examine whether
transforming growth factor-beta 2 ( TGF-beta 2 )
induces the expression of
alpha-smooth muscle actin (SMA) , a biochemical marker of myofibroblasts, in cultured bovine retinal pigment epithelial (RPE) cells ...
TGF-beta 2 induced expression of
alpha-SMA in bovine RPE cells