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ITIH4 — TNF

Text-mined interactions from Literome

Milligan et al., J Neurosci 2001 (Disease Models, Animal...) : Intrathecal gp120 produced time dependent, site-specific increases in TNF and IL-1 protein release into lumbosacral CSF ; parallel cytokine increases in lumbar dorsal spinal cord were also observed
Buriani et al., J NeuroAIDS 1999 : Human immunodeficiency virus type 1 envelope glycoprotein gp120 induces tumor necrosis factor-alpha in astrocytes
Wieseler-Frank et al., Brain Behav Immun 2007 (Pain) : These studies demonstrate that : ( a ) intrathecal gp120 upregulates meningeal gene expression of proinflammatory signals, including tumor necrosis factor-alpha (TNF-alpha), interleukin-1beta (IL-1beta), interleukin 6 (IL-6), and inducible nitric oxide synthase (iNOS), and ( b ) intrathecal gp120 induces meningeal release of TNF-alpha , IL-1beta, and IL-6 ... In addition, stimulation of isolated meninges in vitro with gp120 induced the release of TNF-alpha and IL-1beta, indicating that the resident cells of the meninges are able to respond without immune cell recruitment
Muñoz et al., J Infect Dis 2007 (HIV Infections...) : Progesterone inhibits the induction of TNF synthesis by viral infection and virus or gp-120 induced TNF transcription
Rieckmann et al., J Immunol 1991 (HIV Infections) : Recombinant gp120 specifically enhances tumor necrosis factor-alpha production and Ig secretion in B lymphocytes from HIV infected individuals but not from seronegative donors ... B cells from peripheral blood and lymph nodes of HIV infected individuals spontaneously secreted TNF-alpha ; this secretion was augmented by the presence of gp120, whereas B cells from healthy seronegative donors failed to secrete significant levels of TNF-alpha in the presence or absence of gp120
Chung et al., J Immunol 2012 : Specifically, gp120 inhibited the CpG induced maturation of pDCs and their expression of TNF-a , IL-6, TLR9, IFN regulatory factor 7, and BAFF
Molina et al., J Virol 1990 : Our studies indicate that, in the absence of endotoxin, HIV-1, HIV-2, and HIV gp120 do not induce production of IL-1 beta, IL-6, or TNF-alpha by peripheral blood mononuclear cells
Li et al., J Biol Chem 2013 (MAP Kinase Signaling System) : We show that inhibition of Wnt5a by specific antagonists blocks gp120 induced up-regulation of IL-1ß, IL-6, and TNF-a in the spinal cord
Zembala et al., Clin Immunol Immunopathol 1995 : Hence, FL gp120 may cause TNF release from lymphocytes by binding to CD4, while rp120cd interacts with monocytes but not lymphocytes and induces TNF production by a mechanism not involving CD4 binding
Zembala et al., Immunol Invest 1994 : Thus, induction of TNF by gp120 may be associated with impairment of antigen presenting capacity of monocytes seen in AIDS patients
Kong et al., Cell Immunol 1996 (Inflammation) : Since nitric oxide ( NO ) and proinflammatory cytokines ( TNF-alpha, IL-1, IL-6 ) produced by glial cells have been involved in the neuropathogenesis of various diseases, this study examined the effects of gp120 obtained from two strains, HIV-1IIIB and HIV-1SF2, of the HIV-1 virus on the production of NO, TNF-alpha , IL-1 alpha, IL-1 beta, and IL-6 in murine primary mixed glial cell cultures ... Taken together, these results demonstrate that the production of NO, TNF-alpha , IL-1, or IL-6 from glial cells is differentially regulated by HIV-1IIIB gp120 and HIV-1SF2 gp120
Ilyin et al., Biochem Biophys Res Commun 1997 : Gp120 increased IL-1 beta, IL-1Ra, TNF-alpha , and TGF-beta 1 mRNAs
Kaneko et al., Clin Exp Immunol 1997 (HIV Infections) : On the other hand, inhibition of the mixed lymphocyte reaction (MLR) in CD4+ T cells by gp120, which may be related to gp120 mediated down-regulation of CD4 expression on T cells and activation of protein tyrosine kinase p56 ( lck ) in CD4+ T cells, was observed even in the absence of macrophage derived TNF-alpha induced by gp120
Takeda-Hirokawa et al., Microbiol Immunol 1997 : CRDS treatment of cells not only inhibited the binding of HIV-1 gp120 to CD4+ cells, but also inhibited TNF-alpha production induced by gp120
Catania et al., Peptides 1998 (HIV Infections) : In separate experiments on normal peripheral blood mononuclear cells ( PBMC ), alpha-MSH ( 1-13 ) inhibited production of IL-1 beta and TNF alpha induced by HIV envelope glycoprotein gp 120