Gene interactions and pathways from curated databases and text-mining

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TFRC — TNF

Text-mined interactions from Literome

Speciale et al., J Cell Physiol 2003 (Astrocytoma) : 1-40 Beta-amyloid protein fragment modulates the expression of CD44 and CD71 on the astrocytoma cell line in the presence of IL1beta and TNFalpha
Tchórzewski et al., Med Sci Monit 2005 (Autoimmune Diseases...) : We analyzed reactive oxygen intermediate ( ROI ) production by peripheral blood granulocytes, the production of IL-2, IL-5, IL-10, IL-12, and TNF-alpha cytokines by lymphocytes, and the activation of CD25, CD26, CD69, CD71 , and HLA DR antigen expression
Nanami et al., Arterioscler Thromb Vasc Biol 2005 (Atherosclerosis) : TNF-alpha caused upregulation of TfR and DMT1 and downregulation of FP1, which were demonstrated in mRNA as well as protein levels
Hassan et al., Leuk Res 1991 (Leukemia, Hairy Cell) : TNF induced expression of CD4 and CD71 , increased the intensity of HLA-DR, CD25, CD11c and CD13 expression and decreased both the intensity and frequency of sIg and cIg positivity ... alpha-IFN decreased CD25 expression, the tartrate-resistant acid phosphatase activity ( TRAP ), reduced the TNF induced CD4 and CD71 expression and antagonized the TNF effect on the Ig expression ... The reduction of CD25, TNF induced CD71 and TRAP caused by alpha-IFN seems to represent a deactivation of the activated state of hairy cells ( HCs )
Tsuji et al., J Biol Chem 1991 : Tumor necrosis factor-alpha and interleukin 1-alpha regulate transferrin receptor in human diploid fibroblasts ... We have studied transferrin receptor expression in MRC5 human fibroblasts in response to tumor necrosis factor-alpha ( TNF, cachectin ) or interleukin 1-alpha (IL-1) ... Under these conditions, stimulation of [ 3H ] thymidine incorporation was minimal, suggesting that the induction of transferrin receptor by TNF and IL-1 is mediated by a growth independent regulatory mechanism