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ESR1 — SAFB

Pathways - manually collected, often from reviews:

• NCI Pathway Database Validated nuclear estrogen receptor alpha network: ERA/HET complex (ESR1-SAFB) → ER alpha (ESR1) (modification, collaborate) Oesterreich et al., Mol Endocrinol 2000*
  Evidence: physical interaction
• NCI Pathway Database Validated nuclear estrogen receptor alpha network: ERA/HET complex (ESR1-SAFB) → HET (SAFB) (modification, collaborate) Oesterreich et al., Mol Endocrinol 2000*
  Evidence: physical interaction
• NCI Pathway Database Validated nuclear estrogen receptor alpha network: ER alpha (ESR1) → HET (SAFB) (modification, collaborate) Oesterreich et al., Mol Endocrinol 2000*
  Evidence: physical interaction

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Bind_translation Interaction: ESR1 — SAFB (unspecified method) Oesterreich et al., Mol Endocrinol 2000*
• IRef Biogrid Interaction: ESR1 — SAFB (direct interaction, pull down) Townson et al., J Biol Chem 2004*
• IRef Biogrid Interaction: ESR1 — SAFB (physical association, affinity chromatography technology) Oesterreich et al., Mol Endocrinol 2000*
• IRef Biogrid Interaction: ESR1 — SAFB (direct interaction, pull down) Oesterreich et al., Mol Endocrinol 2000*
• IRef Biogrid Interaction: ESR1 — SAFB (physical association, affinity chromatography technology) Garee et al., Biochem Biophys Res Commun 2011*
• IRef Hprd Interaction: ESR1 — SAFB (in vitro) Oesterreich et al., Mol Endocrinol 2000*
• IRef Hprd Interaction: ESR1 — SAFB (in vivo) Oesterreich et al., Mol Endocrinol 2000*
• IRef Mppi Interaction: ESR1 — SAFB (coimmunoprecipitation) Oesterreich et al., Mol Endocrinol 2000*
• IRef Mppi Interaction: ESR1 — SAFB (copurification) Oesterreich et al., Mol Endocrinol 2000*
• IRef Ophid Interaction: ESR1 — SAFB (aggregation, interologs mapping) Brown et al., Bioinformatics 2005

Text-mined interactions from Literome

Townson et al., J Biol Chem 2004 : We have previously shown that SAFB1 can repress estrogen receptor ( ERalpha ) -mediated transactivation ... We propose a model in which SAFB1 represses ERalpha activity via indirect association with histone deacetylation and interaction with the basal transcription machinery
Jiang et al., Mol Endocrinol 2006 (Breast Neoplasms) : Scaffold attachment factor SAFB1 suppresses estrogen receptor alpha mediated transcription in part via interaction with nuclear receptor corepressor