Gene interactions and pathways from curated databases and text-mining

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IL6 — NPS

Text-mined interactions from Literome

Yamaguchi et al., Inflamm Res 2004 (Neurogenic Inflammation) : Neuropeptides stimulate production of interleukin-1 beta, interleukin-6 , and tumor necrosis factor-alpha in human dental pulp cells
Tatsuno et al., Endocrinology 1991 : We were interested in whether other hypothalamic neuropeptides , which activate adenylate cyclase in the pituitary, also stimulate pituitary IL-6 production
Segat et al., Nanomedicine (Lond) 2011 : Bare ORMOSIL-NPs effectively stimulated the production of IL-1ß/IL-6/TNF-a/IL-8 by monocytes and of IL-8 by polymorphonuclear leukocytes ( PMNs )
Xue et al., Toxicol Lett 2012 (Inflammation...) : In addition, the secretion levels of TNF-a, IL-1ß and IL-6 were variably increased by all four NPs
Yang et al., Int J Nanomedicine 2013 : In addition, the PTX-NPs markedly inhibited interleukin-6 secretion, increased caspase-8, caspase-9, and caspase-3 expression, and induced apoptosis of tumor cells in the treated mice
Komorowski et al., Neuropeptides 1995 : The aim of this study was to evaluate the role of hypothalamic neuropeptides ( thyreoliberin [TRH ], somatostatin [ SRIF ], and gonadoliberin [LH-RH ] ) on the secretion of interleukin-1 beta (IL-1 beta) and interleukin-6 (IL-6) from lipopolysaccharide (LPS) activated human peripheral blood monocytes ( PM ) cultured in vitro
Norris et al., J Immunol 1994 (Second Messenger Systems) : IL-6 gene expression in astrocytes is regulated by cytokines, infectious agents, neuropeptides , and neurotransmitters, and most of these stimuli interact synergistically
Lieb et al., J Neuroimmunol 1996 : Effects of substance P and selected other neuropeptides on the synthesis of interleukin-1 beta and interleukin-6 in human monocytes : a re-examination
Cai et al., Endocrinology 1997 : Regulation of Interleukin-6 (IL-6) production in bone marrow ( BM ) -derived stromal cells by neuropeptides , pituitary adenylate cyclase activating polypeptide ( PACAP ) and vasoactive intestinal peptide (VIP), was examined