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BRCA1 — SUMO1

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

• IRef Biogrid Interaction: BRCA1 — SUMO1 (physical association, affinity chromatography technology) Morris et al., Nature 2009*
• IRef Biogrid Interaction: BRCA1 — SUMO1 (direct interaction, fluorescent resonance energy transfer) Morris et al., Nature 2009*
• IRef Biogrid Interaction: BRCA1 — SUMO1 (direct interaction, two hybrid) Park et al., Nucleic Acids Res 2008*
• IRef Biogrid Interaction: BRCA1 — SUMO1 (physical association, affinity chromatography technology) Park et al., Nucleic Acids Res 2008*
• IRef Biogrid Interaction: BRCA1 — SUMO1 (direct interaction, pull down) Park et al., Nucleic Acids Res 2008*
• IRef Dip Interaction: BRCA1 — SUMO1 (direct interaction, fluorescent resonance energy transfer) Morris et al., Nature 2009*
• IRef Dip Interaction: BRCA1 — SUMO1 (direct interaction, pull down) Morris et al., Nature 2009*
• IRef Dip Interaction: BRCA1 — SUMO1 (direct interaction, anti bait coimmunoprecipitation) Morris et al., Nature 2009*

Text-mined interactions from Literome

Park et al., Nucleic Acids Res 2008 : Consistently, silencing of SUMO1 led to recruitment of BRCA1 and release of HDAC1 at the BRCA1 target promoters, and subsequent transcriptional activation of the BRCA1 target genes
Morris et al., Nature 2009 : PIAS SUMO E3 ligases co-localize with and modulate SUMO modification of BRCA1, and are required for BRCA1 ubiquitin ligase activity in cells