Gene interactions and pathways from curated databases and text-mining

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BDNF — GFAP

Text-mined interactions from Literome

Chidlow et al., Molecular vision 2005 (Optic Nerve Injuries) : Administration of BDNF resulted in a substantial, but not complete, preservation of the levels of the RGC specific mRNAs, while ONT induced increases in GFAP and trophic factor mRNAs were not reduced to any great extent by BDNF
Okuyama et al., Neurosci Lett 2012 (Ischemic Attack, Transient) : In the present study using a transient global ischemia mouse model, we showed that ( 1 ) a citrus flavonoid 3,5,6,7,8,3',4'-heptamethoxyflavone ( HMF ) induced the phosphorylation of extracellular signal regulated kinases 1/2 ( ERK1/2 ) and cAMP response element binding protein ( CREB ) in the hippocampus after ischemia ; ( 2 ) HMF increased the expression of brain derived neurotrophic factor (BDNF) , a representative neurotrophic factor in the central nervous system, in the hippocampal dentate gyrus, and most BDNF positive cells were also stained with anti-glial fibrillary acidic protein ( one of the major intermediate filament proteins of mature astrocytes ) and ( 3 ) HMF increased doublecortin positive neuronal precursor cells in the dentate gyrus subventricular zone or subgranular zone