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ANGPT2 — TP53
Text-mined interactions from Literome
Mueller et al., Circulation 2002
:
Overexpression of antisense Id3 abrogated the
effect of
Ang II on the expression of p21 ( WAF1/Cip1 ), p27 ( Kip1 ), and
p53
Min et al., Cardiovasc Res 2007
:
Persistent
Ang II ( 100 nM ) stimulation increased SA-beta-gal stained VSMC and
enhanced expression of p21,
p53 , p16, p27 and Ki-ras2A
Liu et al., Toxicol Lett 2009
:
The present study was to investigate whether
Ang II induces
p53 expression and activation and if so, whether Ang II-induced cardiac cell death is p53 dependent, and whether a potent antioxidant metallothionein ( MT ) prevents Ang II-induced p53 expression, and associate apoptotic cell death signaling