◀ Back to FOS
FOS — STAT1
Pathways - manually collected, often from reviews:
-
FastForward regulation:
STAT1
→
FOS
(transcriptional regulation, unknown)
Ehret et al., J Biol Chem 2001*, Murai et al., Mol Cell Biol 2002, Schreiner et al., J Biol Chem 2002, Yang et al., J Biol Chem 2003*
Evidence: DNABINDING
-
FastForward regulation:
STAT1
→
FOS
(transcriptional regulation, unknown)
Eilers et al., Mol Cell Biol 1994*
Evidence: DNABINDING
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Lo et al., Cell Signal 2006
:
Collectively, our results demonstrate for the first time that stimulation of Galpha(16) can lead to
STAT1 dependent
c-Fos transcriptional activation via PLCbeta, c-Src/JAK and ERK pathways
Kamiya et al., Immunol Lett 2011
:
In addition, IL-27 was recently demonstrated to not only inhibit Th17 differentiation but also directly act on osteoclast precursor cells and suppress RANKL mediated osteoclastogenesis through
STAT1 dependent inhibition of
c-Fos , leading to amelioration of the inflammatory bone destruction