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Liu et al., Int J Cancer 2010 (Anoxia...) : ERK/MAPK activation involves hypoxia induced MGr1-Ag/37LRP expression and contributes to apoptosis resistance in gastric cancer
Liu et al., Cancer Sci 2010 (Neoplasm Invasiveness...) : Both ERK and JNK inhibitors significantly inhibited hypoxia induced expression of 67LR and the subsequent expression of uPA and MMP 9 ... Taken together, these results reveal that 67LR promotes the invasive and metastatic ability of the gastric cancer cells through increasing uPA and MMP 9 expression, with involvement of the ERK and JNK signal pathway in hypoxia induced 67 LR expressions and subsequent uPA and MMP9 expression