Gene interactions and pathways from curated databases and text-mining

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FAS — LPL

Text-mined interactions from Literome

Michaud et al., Diabetes 2001 : In the present study, we evaluated the direct effect of FAs on murine Mo LPL expression and examined the involvement of peroxisome proliferator activated receptors ( PPARs ) in this effect ... To evaluate the role of PPARs in the modulatory effect of FAs on Mo LPL gene expression, DNA binding assays were performed ... Overall, these results provide the first evidence for a direct regulatory effect of FAs on Mo LPL and suggest a potential role of PPARs in the regulation of Mo LPL gene expression by FAs
Ranganathan et al., J Lipid Res 2006 (Insulin Resistance...) : After pioglitazone treatment, DGAT1 expression was increased by 33 +/- 10 % ( P < 0.05 ) and FAS expression increased by 63 +/- 8 % ( P < 0.05 ) ; however, LPL expression was not altered