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Text-mined interactions from Literome

Parmentier et al., Eur Respir J 2000 : NAC ( 5 mM ) also enhanced LPS induced IL-1beta release from THP-1 cells ( p < 0.001 ) ... In addition, treatment of cells with cycloheximide, an inhibitor of protein synthesis, inhibited the NAC mediated IL-1beta release
Mathy-Hartert et al., Osteoarthritis Cartilage 2002 (Osteoarthritis, Knee) : Interestingly, NAC increased the IL-1beta and iNOS mRNA levels but did not significantly modify COX-2 mRNA expression
Kao et al., Clin Exp Pharmacol Physiol 2006 (Body Weight...) : In addition, NAC diminished the LPS induced increases in nitrate/nitrite, MG, TNF-a and IL-1b
Kwon et al., Life Sci 2007 : IL-1 beta release and caspase-1 activity induced by DSS were significantly inhibited by a MAPK kinase 1/2 inhibitor, a p38 MAPK inhibitor, and NAC , however, not by JNK1/2 or a protein kinase C inhibitor
Hu et al., J Toxicol Environ Health 2007 : The secretion of IL-1beta and TNF-alpha by silica exposed AM was markedly inhibited by NAC and R6G, suggesting that the production of these cytokines is also ROS dependent
Geudens et al., J Heart Lung Transplant 2007 (Disease Models, Animal...) : NAC administered prior to hilar clamping led to a significant decrease in macrophages and lymphocytes and interleukin (IL)-1 beta levels after ischemia ... NAC also resulted in significantly fewer macrophages, lymphocytes and neutrophils as well as IL-1 beta , keratinocyte cytokine ( KC ), monocyte chemoattractant protein (MCP)-1 and IL-6 levels in BAL taken after reperfusion
Liu et al., Mol Biol Rep 2009 (Myocardial Infarction) : NAC inhibits the pro-inflammatory factors expressions ( TNF-alphaand IL-1beta ) stimulated by ISO