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EGR1 — FUT1
Protein-Protein interactions - manually collected from original source literature:
Studies that report less than 10 interactions are marked with *
Text-mined interactions from Literome
Li et al., Zhonghua Gan Zang Bing Za Zhi 2005
:
Gel shift study showed that stimulation of
HSC by Aldo markedly
increased the
EGR-1 DNA binding activity, which was abrogated by U0126, reaching a maximum at 60 minutes, and then declined progressively ...
Stimulation of
HSC by Aldo results in activation of
EGR-1 via ERK1/2 pathway, leading to up-regulation of PDGF-B expression
Fu et al., Biochem Pharmacol 2006
:
Taken together, our results demonstrate that EGCG suppresses gene expression of EGFR in rat activated
HSC in vitro
mediated by reducing the trans-activation activity of
Egr-1
Zhou et al., Life Sci 2009
:
Further investigation reveals that Egr-1 exerts a clear inhibitory effect on the promoter activity and expression of PPARgamma gene and demonstrates that
Egr-1 increases the expression of
HSC activation markers and promotes HSC growth