Gene interactions and pathways from curated databases and text-mining

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CDC20 — CDK2

Protein-Protein interactions - manually collected from original source literature:

Studies that report less than 10 interactions are marked with *

Text-mined interactions from Literome

Heo et al., Curr Genet 1999 : Hence, SCC1/MCD1/RHC21 is positively regulated by the mitotic CDK , CDC28
Yamada et al., J Biol Chem 2011 : CDK2 , but not CDC2, suppressed the interaction of p21Cip1 with Cdc20 , thereby leading to inhibition of anaphase promoting complex/cyclosome and its activator Cdc20 ( APC/CCdc20 ) -mediated p21Cip1 ubiquitylation
Cocklin et al., PloS one 2011 : Cell division is controlled in part by the timely activation of the CDK , Cdc28 , through its association with G1 and G2 cyclins
Jallepalli et al., Genes Dev 1996 : Rum1 and Cdc18 link inhibition of cyclin dependent kinase to the initiation of DNA replication in Schizosaccharomyces pombe
Sutton et al., Genetics 1997 : The CAK1 gene encodes the major CDK activating kinase (CAK) in budding yeast and is required for activation of Cdc28p for cell cycle progression from G2 to M phase