UCSC Genome Browser Gene Interaction Graph

JavaScript is disabled in your web browser

You must have JavaScript enabled in your web browser to use the Genome Browser

Gene interactions and pathways from curated databases and text-mining

◀ Back to SDC2

PTPN11 — SDC2

Pathways - manually collected, often from reviews:

NCI Pathway Database FGF signaling pathway: GRB2 (GRB2) → SHP2/GAB1/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database FGF signaling pathway: Gab1 (GAB1) → SHP2/GAB1/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database FGF signaling pathway: SHP2 (PTPN11) → FGFR/FGF/Syndecan-2/FRS2 complex (SDC2-FRS2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database FGF signaling pathway: SHP2 (PTPN11) → SHP2/GAB1/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database FGF signaling pathway: FGFR/FGF/Syndecan-2/FRS2 complex (SDC2-FRS2) → SHP2/GAB1/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database SHP2 signaling: GRB2 (GRB2) → SHP2/GAB/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database SHP2 signaling: Gab1 (GAB1) → SHP2/GAB/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database SHP2 signaling: SHP2 (PTPN11) → FGFR/FGF/Syndecan-2/FRS2 complex (SDC2-FRS2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database SHP2 signaling: SHP2 (PTPN11) → SHP2/GAB/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay
NCI Pathway Database SHP2 signaling: FGFR/FGF/Syndecan-2/FRS2 complex (SDC2-FRS2) → SHP2/GAB/GRB2/FRS2/FGFR/FGF/Syndecan-2 complex (PTPN11-GAB1-GRB2-FRS2-SDC2) (modification, collaborate)
Ong et al., Proc Natl Acad Sci U S A 2001, Agazie et al., Oncogene 2003, Gotoh et al., Proc Natl Acad Sci U S A 2004, Kanai et al., J Biol Chem 1997
Evidence: mutant phenotype, assay