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GPI — IL2

Text-mined interactions from Literome

Matkó et al., Eur J Biochem 2002 (Leukemia, T-Cell...) : Rafts may promote rapid formation of a high affinity IL-2R complex, even at low levels of IL-2 stimulus, and may also form a platform for the regulation of IL-2 induced signals by GPI-proteins ( e.g. CD48 )
Chen et al., J Interferon Res 1992 : We investigated the augmenting effect of mouse recombinant interferon-beta ( MurIFN-beta ) on the induction of macrophage ( M phi ) cytolytic activity by interleukin-2 (IL-2) ... MurIFN-beta showed a dose dependent enhancement on the induction of anti-M phi activity by IL-2 with a peak at 2,000-10,000 U/ml, and the augmenting effect of rIFN-beta was more marked on lower doses of rIL-2 than on higher doses ... This augmenting effect was also observed in IFN-alpha, whereas IFN-gamma showed no influence on IL-2 induced anti-M phi activity
Yoshimura et al., Transplantation 1991 : To dissect the immunosuppressive activity of AMF, the effect of AMF on cytokine production and interleukin 2 (IL-2) receptor expression of concanavalin A-stimulated lymphocytes were investigated ... AMF suppressed interferon and IL-2 production ... Interestingly, however, AMF did not suppress interleukin 3 (IL-3) and interleukin 6 (IL-6) production, as well as IL-2 receptor expression
Klarnet et al., J Immunol 1989 : Stimulation with FBL alone in the absence of M phi or IL-1 was sufficient for induction of IL-2R expression, and rendered cells responsive to IL-2, but M phi or IL-1 were also required to induce production of IL-2
Mills et al., J Biol Chem 1985 : In this study, we established that IL 2 produces an increase in pHi and determined whether this increase in pHi plays a role in the proliferative response to IL 2 ... Monitoring pHi with an intracellularly trapped, pH-sensitive, fluorescent dye, 2',7'-bis ( carboxyethyl ) -5,6-carboxyfluorescein, we demonstrated that IL 2 rapidly ( less than 90 s ) initiates an increase in pHi in IL 2-sensitive human and murine T cells
Frasier-Scott et al., J Clin Invest 1988 : Both purified natural IL-2 ( nIL-2 ) and rIL-2 induced significant PGI2 synthesis ... We conclude that IL-2 stimulated sustained PGI2 production by a mechanism that includes the de novo synthesis of PGH synthase
Sasaki et al., Blood 1997 (Hematologic Neoplasms...) : Phorbol 12-myristate 13-acetate ( PMA ), interleukin-1 (IL-1), IL-3, IL-6, granulocyte-macrophage colony stimulating factor ( GM-CSF ), thrombopoietin (TPO), and tumor necrosis factor-alpha (TNF-alpha) enhanced PGI2-R mRNA expression