Gene interactions and pathways from curated databases and text-mining

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IL2 — TNC

Text-mined interactions from Literome

Doi et al., Eur J Immunol 1991 : We show here that TNC induced the growth of the fetal double negative thymocytes in the presence of recombinant interleukin 2 ( rIL2 )
Maqbool et al., Matrix Biol 2013 : ECM-regulatory matricellular proteins are synthesized by several myocardial cell types including CF. We investigated the effects of pro-inflammatory cytokines on matricellular protein expression in cultured human CF. cDNA array analysis of matricellular proteins revealed that interleukin-1a ( IL-1a, 10ng/ml, 6h ) down-regulated connective tissue growth factor ( CTGF/CCN2 ) mRNA by 80 % and up-regulated tenascin-C (TNC) mRNA levels by 10-fold in human CF, without affecting expression of thrombospondins 1-3, osteonectin or osteopontin
Gao et al., Immunol Lett 1993 : Furthermore, we demonstrated that TNC-R3.1 could support the differentiation of CD3+CD4+CD8- or CD3+CD4-CD8+ thymocytes from CD3-CD4-CD8- thymocytes in the presence of IL-7 and IL-2