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ACKR3 — IL8

Pathways - manually collected, often from reviews:

• Reactome Reaction: ACKR3 → IL8 (reaction) Lambert et al., Science signaling 2008, Lerea et al., Neuron 1989, Van Dop et al., Nucleic Acids Res 1989, Itoh et al., J Biol Chem 1988, Takami et al., Brain Res Mol Brain Res 1994

Text-mined interactions from Literome

Wang et al., J Biol Chem 2008 (Neoplasm Metastasis...) : CXCR7/RDC1 also regulates the expression of the proangiogenic factors interleukin-8 or vascular endothelial growth factor, which are likely to participate in the regulation of tumor angiogenesis
Singh et al., Cancer Res 2011 (Prostatic Neoplasms) : The IL-8 regulated chemokine receptor CXCR7 stimulates EGFR signaling to promote prostate cancer growth ... Here we report that the procancerous cytokine IL-8 ( interleukin-8 ) upregulates CXCR7 expression along with ligand independent functions of CXCR7 that promote the growth and proliferation of human prostate cancer cells ( CaP cells )