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Gu et al., Oncogene 2005
(Brain Neoplasms...) :
Consistent with these results, EphA8 expression induced a sustained increase in the activity of MAPK , whereas ligand mediated EphA8 activation had no further modulatory effects on MAP kinase activity
Day et al., Cancer Cell 2013
(Brain Neoplasms...) :
Importantly, EphA3 is highly expressed on the tumor initiating cell population in glioma and appears critically involved in maintaining tumor cells in a less differentiated state by modulating mitogen activated protein kinase signaling