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IFI44 — MUC5AC

Text-mined interactions from Literome

Takeyama et al., J Immunol 2000 (MAP Kinase Signaling System) : Neutrophil supernatant induced EGFR tyrosine phosphorylation, activation of p44/42mapk , and MUC5AC synthesis were inhibited by antioxidants ( N-acetyl-cysteine, DMSO, dimethyl thiourea, or superoxide dismutase ) ; neutralizing Abs to EGFR ligands ( EGF and TGF-alpha ) were without effect, and no TGF-alpha protein was found in the neutrophil supernatant ... In contrast, the EGFR ligand, TGF-alpha, increased EGFR tyrosine phosphorylation, activation of p44/42mapk , and subsequent MUC5AC synthesis, but these effects were not inhibited by antioxidants
Inoue et al., Respir Physiol Neurobiol 2006 (Cadaver...) : An inhibitor of the nuclear factor kappaB caffeic acid phenylethyl ester, inhibitors of selective p44/42 mitogen activated protein kinase-kinase PD98059 and U0126, and a selective Src inhibitor PP1 attenuated MUC5AC mRNA expression, and secretion and production of MUC5AC and total mucin glycoprotein in the surface cells