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E2F4 — PHB

Text-mined interactions from Literome

Wang et al., Oncogene 1999 : Surprisingly, prohibitin mediated repression of E2F could not be reversed by adenovirus E1A protein ... A prohibitin mutant that could not bind to Rb was impaired in its ability to repress E2F activity and inhibit cell proliferation
Wang et al., Mol Cell Biol 1999 : We recently observed that prohibitin , a potential tumor suppressor protein, binds to the retinoblastoma ( Rb ) protein and represses E2F transcriptional activity ... Prohibitin was also found to interact with the signaling kinase c-Raf-1, and Raf-1 could effectively reverse prohibitin mediated repression of E2F activity
Wang et al., EMBO J 2002 : Expression of a dominant negative Brg-1 or Brm releases prohibitin mediated repression of E2F and relieves prohibitin mediated growth suppression
Fusaro et al., J Biol Chem 2003 : Prohibitin , a potential tumor suppressor protein, has been shown to inhibit cell proliferation and repress E2F transcriptional activity