Mirmohammadsadegh et al., J Invest Dermatol 2006
(Melanoma) :
Inhibition of Stat5b expression by small interfering RNA strongly reduced the expression of Bcl-2 and led to decreased cell viability and increased apoptosis in the melanoma cell lines A375 and BLM
Jinawath et al., PloS one 2010
(Ovarian Neoplasms) :
Combined ectopic expression of RELA and STAT5B enhanced Bcl-xL promoter activity while treatment with BMS-345541 and Dasatinib decreased it