Gene interactions and pathways from curated databases and text-mining

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ADCYAP1 — RAC1

Text-mined interactions from Literome

Sakai et al., Brain Res Mol Brain Res 2004 (MAP Kinase Signaling System) : PACAP activates Rac1 and synergizes with NGF to activate ERK1/2, thereby inducing neurite outgrowth in PC12 cells ... PACAP induced transient activation of Rac1 , a small GTPase involved in neurite outgrowth, in a PI3-kinase independent manner, and stimulated accumulation of active Rac1 at filamentous actin-rich protrusions on the cell surface to induce subsequent neurite formation
Lazarovici et al., J Mol Neurosci 2012 (Hypoxia-Ischemia, Brain...) : PACAP38 induced stimulation of Rac and suppression of Rho GTPase activities