◀ Back to GSK3B

CDC42 — GSK3B

Text-mined interactions from Literome

Etienne-Manneville et al., Nature 2003 : Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity ... Cdc42 dependent phosphorylation of GSK-3beta occurs specifically at the leading edge of migrating cells, and induces the interaction of adenomatous polyposis coli (Apc) protein with the plus ends of microtubules
Crean et al., FASEB J 2004 : These data highlight for the first time an integrated mechanism whereby CTGF regulates cell migration through facilitative actin cytoskeleton disassembly, which is mediated by dephosphorylation of focal adhesion kinase and paxillin, loss of RhoA activity, activation of Cdc42 , and phosphorylation of PKC-zeta and GSK-3beta
Jin et al., Neurochem Int 2007 : These results suggest that the NGF induced ruffling requires activation of Rac1 and Cdc42 , but does not require Ras, PI-3k, Akt and GSK-3beta