Gene interactions and pathways from curated databases and text-mining

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GNRHR — PRL

Text-mined interactions from Literome

Smith et al., Endocrinology 1989 : Inhibition of suckling induced PRL secretion with CB-154 caused a 2-fold increase in GnRH-R , and this effect could be completely reversed by simultaneous treatment with ovine PRL
Duncan et al., Endocrinology 1986 : We conclude that in female rats, the presence of both E2 and a low serum PRL level is necessary for GnRH to increase GnRH-R , and the interaction of these factors may be involved in the regulation of GnRH-R during the estrous cycle
Pieper et al., Endocrinology 1984 : Suppression of PRL secretion by bromocryptine resulted in augmented GnRH-R responses to GnRH, and GnRH-R concentrations rose to the same values induced in males