UCSC Genome Browser Gene Interaction Graph

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Gene interactions and pathways from curated databases and text-mining

◀ Back to PRKCB

JUND — PRKCB

Pathways - manually collected, often from reviews:

OpenBEL Selventa BEL large corpus: JUND → Calcium/Diacylglycerol/PRKCB complex (PRKCB) (increases)

Evidence: FceRI stimulation induced a reduced production of IL-6 mRNA and protein in PKCb -/- mast cells (14), which is consistent with an increased accumulation of IL-6 mRNA in PKCb-overexpressing mast cells (15). Since PKCb (and PKCe) can be involved in FceRI-induced expression of c-fos and c-jun mRNAs (16), reduced induction of JunD mRNA may contribute to the reduced IL-6 production in PKCb -/- mast cells.