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ESR1 — PCNA

Pathways - manually collected, often from reviews:

• NCI Pathway Database Validated nuclear estrogen receptor alpha network: E2/ERA (dimer) complex (ESR1) → PCNA (PCNA) (modification, collaborate) Schultz-Norton et al., Nucleic Acids Res 2007*
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database Validated nuclear estrogen receptor alpha network: E2/ERA (dimer) complex (ESR1) → E2/ERA (dimer)/PCNA complex (ESR1-PCNA) (modification, collaborate)
  Schultz-Norton et al., Nucleic Acids Res 2007*
  Evidence: mutant phenotype, physical interaction
• NCI Pathway Database Validated nuclear estrogen receptor alpha network: PCNA (PCNA) → E2/ERA (dimer)/PCNA complex (ESR1-PCNA) (modification, collaborate)
  Schultz-Norton et al., Nucleic Acids Res 2007*
  Evidence: mutant phenotype, physical interaction

Text-mined interactions from Literome

Clark et al., Mol Cell Biol 2000 : In particular, hormonal activation of a conditional v-Jun-estrogen receptor fusion protein in quiescent, growth factor deprived cells stimulates cyclin E-cdk2 activity and triggers Rb phosphorylation and DNA synthesis
Tekmal et al., J Steroid Biochem Mol Biol 2005 (Hyperplasia) : Lack of ERalpha expression in the aromatase/ERKO mice resulted in a decrease in the expression of Cyclin D1, PCNA and TGFbeta relative to the aromatase parental strain
Wang et al., Cancer Res 2005 (Breast Neoplasms...) : Cyclin D1 expression enhanced ERalpha recruitment to an ERE
Schultz-Norton et al., Nucleic Acids Res 2007 : We show that PCNA interacts with ERalpha in the absence and in the presence of DNA, enhances the interaction of ERalpha with ERE containing DNA, and associates with endogenous estrogen-responsive genes