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SLC22A3 — SNAI1

Text-mined interactions from Literome

Lindsley et al., Cell stem cell 2008 : Transient Mesp1 expression in ESCs promotes changes associated with epithelial-mesenchymal transition (EMT) and induction of Snai1 , consistent with a role in gastrulation
Peña et al., Oncogene 2009 (Carcinoma...) : SNAI1 , ZEB1, E-cadherin ( CDH1 ), and vitamin D receptor (VDR) genes regulate the epithelial-mesenchymal transition (EMT) that initiates the invasion process of many tumor cells ... These results indicate that histologically normal tissue adjacent to tumor tissue expressing the EMT inducing gene SNAI1 shows alterations in the expression of epithelial differentiation genes such as CDH1 and VDR
Jayachandran et al., Thorax 2009 (Disease Models, Animal...) : Using quantitative reverse transcription-PCR ( RT-PCR ), immunofluorescence, immunohistochemistry, western blotting, as well as gain- and loss-of-function studies and functional assays, the role of SNAI1 and SNAI2 in TGFbeta1 induced EMT in ATII cells in vitro was assessed ; and the expression of SNAI transcription factors was analysed in experimental and human IPF in vivo ... SNAI overexpression was sufficient to induce EMT, and small interfering RNA ( siRNA ) -mediated SNAI depletion attenuated TGFbeta1 induced ATII cell migration and EMT
Hoshino et al., Biochem Biophys Res Commun 2009 (Colorectal Neoplasms...) : Previous reports have demonstrated that SNAI1 plays a role in epithelial-mesenchymal transition (EMT) through the suppression of CDH1
Schwock et al., BMC clinical pathology 2010 : SNAI1 can initiate epithelial-mesenchymal transition (EMT) , leading to loss of epithelial characteristics and, in cancer, to invasion and metastasis
Nagai et al., Mol Cancer Ther 2011 (Carcinoma, Hepatocellular...) : The knockdown of SNAI1 using siRNA canceled the HGF mediated morphologic changes and cadherin switching, indicating that SNAI1 is required for the HGF mediated EMT in HCC
You et al., Invest Ophthalmol Vis Sci 2012 (Disease Models, Animal...) : Expression of vimentin and the transcription factor Snai1 , a master regulator of EMT , was determined by RT-PCR, Western blotting analysis, and immunofluorescence
Guo et al., Asian Pac J Cancer Prev 2011 (Lymphatic Metastasis...) : The zinc-finger factor Snai1 plays an important role in the down-regulation of E-cadherin expression and in the induction of epithelial-mesenchymal transition (EMT) during cancer progression
Ramadoss et al., J Biol Chem 2012 (Breast Neoplasms) : Here we report that KDM6B played a permissive role in TGF-ß induced EMT in mammary epithelial cells by stimulating SNAI1 expression
Zheng et al., PloS one 2012 (Carcinoma, Hepatocellular...) : The transcription factor GLI1 mediates TGFß1 driven EMT in hepatocellular carcinoma via a SNAI1 dependent mechanism