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EPHB2 — UTS2

Text-mined interactions from Literome

Zou et al., FEBS Lett 2001 (Cardiomegaly) : ERK activation by UII at 100 nM peaked at 8 min after stimulation
Tamura et al., Life Sci 2003 : On the other hand, UII induced an increase in the phosphorylation level of ERK , but not FAK, in cells adherent to fibronectin ... Our results suggested that activation of integrin mediated signaling pathways play a critical role in UII induced phosphorylation of ERK , leading to proliferation of VSMCs, which does not involved increased phosphorylation of FAK
Ziltener et al., J Recept Signal Transduct Res 2002 (Calcium Signaling) : Urotensin II mediates ERK1/2 phosphorylation and proliferation in GPR14 transfected cell lines
Matsushita et al., Endocrinology 2003 : To investigate whether UII acts as an autocrine/paracrine growth factor for renal epithelial cells, we have studied the effects of human UII ( hUII ) on DNA synthesis, cytosolic free Ca ( 2+ ) concentration ( [ Ca ( 2+ ) ] ( i ) ), ERK activation, and protooncogene (c-myc) expression in a porcine renal epithelial cell line ( LLCPK1 )
Onan et al., Mol Endocrinol 2004 (Cardiomegaly) : Urotensin II potently activated the MAPKs, ERK1/2 and p38, and blocking these kinases with PD098059 and SB230580, respectively, significantly inhibited urotensin II-mediated hypertrophy
Matsusaka et al., Naunyn Schmiedebergs Arch Pharmacol 2006 : Stress-fiber formation and ERK ( p44/p42 ) activity were also increased by UII