Gene interactions and pathways from curated databases and text-mining

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NGF — SCG2

Text-mined interactions from Literome

Chou et al., Brain Res Mol Brain Res 2000 : Wnt-1 decreased the NGF induced expression of the late-response gene SCG10 but not of the immediate early genes, fos, Nur77 and UPAR ( urokinase-type plasminogen activator receptor ) nor of the late-response genes GAP-43 and collagenase
Laslop et al., Neuroscience 1992 : Effects of nerve growth factor on the biosynthesis of chromogranin A and B, secretogranin II and carboxypeptidase H in rat PC12 cells ... Effects of nerve growth factor on the biosynthesis of chromogranin A and B, secretogranin II and carboxypeptidase H in rat PC12 cells
Sigmund et al., J Biol Chem 1990 (Adrenal Gland Neoplasms...) : Effect of nerve growth factor and fibroblast growth factor on SCG10 and c-fos expression and neurite outgrowth in protein kinase C-depleted PC12 cells ... Activators of PKC such as phorbol 12-myristate 13-acetate ( PMA ) or 1-oleoyl 2-acetyl glycerol mimicked the stimulatory effect of NGF and bFGF on SCG10 mRNA levels
Stein et al., Dev Biol 1988 (Pheochromocytoma) : The induction of a neural-specific gene, SCG10 , by nerve growth factor in PC12 cells is transcriptional, protein synthesis dependent, and glucocorticoid inhibitable ... NGF , FGF, and, to a lesser extent, phorbol esters induced SCG10 , whereas EGF and dibutyryl cAMP did not
Burnham et al., Dev Biol 1994 : In this study we examined further the capability of CNTF to support neonatal rat superior cervical ganglion ( SCG ) sympathetic neurons in vitro and the effect of CNTF on the trophic activities of NGF
Mori et al., Age Ageing 1993 : Studies of the induction of SCG10 by NGF in PC12 cells suggest that transcriptional inducible element ( s ) are present, at least in part, in the upstream region of the SCG10 gene
Scammell et al., Brain Res Mol Brain Res 1995 : Whereas NGF alone modestly increased SgII mRNA expression in PC12 cells ( 1.8-fold above control ), it did not uncover a stimulatory effect of FSK or PMA
Scalapino et al., Exp Neurol 1996 : In the current investigation we have used transplants of NGF dependent neonatal superior cervical ganglion ( SCG ) neurons to investigate the influence of NGF and septal denervation ( either alone or in combination with one another ) upon neuronal survival and intrahippocampal sprouting