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ARHGEF7 — PLCG1

Pathways - manually collected, often from reviews:

• NCI Pathway Database Regulation of CDC42 activity: None → PLCgamma1/betaPIX/GIT1 complex (PLCG1-ARHGEF7-GIT1) (modification, collaborate)
  Jones et al., Mol Cell Biol 2007*
  Evidence: mutant phenotype, assay, physical interaction
• NCI Pathway Database Regulation of CDC42 activity: CDC42/GDP complex (CDC42) → PLCgamma1/betaPIX/GIT1 complex (PLCG1-ARHGEF7-GIT1) (modification, collaborate)
  Jones et al., Mol Cell Biol 2007*
  Evidence: mutant phenotype, assay, physical interaction

Text-mined interactions from Literome

Bae et al., J Cell Biochem 2005 (Breast Neoplasms) : BetaPix-a enhances the activity of phospholipase Cgamma1 by binding SH3 domain in breast cancer
Jones et al., Mol Cell Biol 2007 : The association of PLCgamma1 with the complex requires both GIT1 and beta-Pix and the specific array region ( gammaSA ) of PLCgamma1