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EPHB2 — FCGR2A
Text-mined interactions from Literome
Hazan-Halevy et al., J Biol Chem 2000
:
Cross linking of
FcgammaRIIA or FcgammaRIIIB
induces p38 mitogen activated protein ( MAP ) kinase and
extracellular regulated kinase (ERK) phosphorylation
Coxon et al., J Immunol 2000
:
Homotypic and heterotypic cross linking of
Fc gamma RIIa and/or Fc gamma RIIIb
resulted in a rapid, transient increase in
ERK and p38 activity, with maximal stimulation between 1 and 3 min. Fc gamma RIIa and Fc gamma RIIIb stimulated distinct patterns of ERK and p38 activity, and heterotypic cross linking failed to stimulate synergistic activation of either ERK or p38 activity ... Our data indicate that
Fc gamma RIIa and Fc gamma RIIIb independently
activate ERK and p38
García-García et al., J Immunol 2007
(MAP Kinase Signaling System) :
WT
FcgammaRIIA and mutants that associated with lipid rafts efficiently activated NF-kappaB, in an
ERK dependent manner
García-García et al., J Immunol 2009
:
FcgammaRIIIB, but not
FcgammaRIIA ,
promoted a robust increase in phosphorylated
ERK in the nucleus, and also efficient phosphorylation of the NF Elk-1