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EPHB2 — SLC9A3R2

Text-mined interactions from Literome

Jung Kang et al., Cell Signal 2004 : NHERF2 increases platelet derived growth factor induced proliferation through PI-3-kinase/Akt-, ERK- , and Src family kinase dependent pathway ... In contrast, the NHERF2 dependent increase of ERK phosphorylation was not affected by pretreatment with PD98059 in Rat1/NHERF2 cells ... Thus, the NHERF2 dependent increase of ERK phosphorylation occurs in a MEK independent fashion ... Pretreatment with PP2, a specific inhibitor of Src family tyrosine kinase, completely blocked the NHERF2 dependent increase of the phosphorylation of ERK and Akt, suggesting that NHERF2 up-regulates Erk phosphorylation through a Src family kinase dependent pathway
Oh et al., Mol Cell Biol 2004 : In addition, NHERF2 increases LPA induced ERK activation, which is followed by cyclooxygenase-2 induction via a PLC dependent pathway