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FAS — GLA
Text-mined interactions from Literome
Menendez et al., Int J Oncol 2004
(Breast Neoplasms) :
Western blotting studies showed that down-regulation of FAS protein expression tightly correlated with previously observed inhibition of FAS activity, suggesting that ALA-, DHA-, and
GLA induced changes in
FAS activity resulted from effects at the protein level
Menendez et al., Med Hypotheses 2005
(Breast Neoplasms) :
Second,
GLA-epoxide inhibits
FAS activity, thus resulting in the accumulation of cytosolic malonyl-CoA which, in turn, inhibits carnitine palmitoyl transferase I ( CPT-I ) and prevents FA oxidation