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CDKN1A — RB1CC1

Text-mined interactions from Literome

Melkoumian et al., Cancer Res 2005 (Breast Neoplasms) : Consistent with the G1 arrest induced by FIP200, we found that FIP200 increased p21 and decreased cyclin D1 protein levels in breast cancer cells ... In addition, FIP200 significantly induced p21 promoter activity in MCF-7 cells and this response was abolished upon deletion of p53 binding sites within p21 promoter
Martin et al., Mol Cell Biol 2008 : Conversely, FIP200 enhances the transcriptional activation of the p21 promoter by PIASy whereas PIASy transcription activity is severely reduced upon FIP200 depletion by RNA interference
Chano et al., PloS one 2010 (Neoplasms) : The nuclear RB1CC1 complex involving hSNF5 and/or p53 activated transcription of RB1, p16 and p21 , and suppressed tumor cell growth