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IL12B — VEGFA
Text-mined interactions from Literome
Matsumoto et al., Nephron 2000
(Nephrosis, Lipoid) :
Taken together, our results indicate that both IL-18 and
IL-12 contribute to the
VPF production in vitro and suggest that they play key roles in the complexity of cytokine regulation in the pathophysiology of VPF
Nakayama et al., Anticancer Res 2000
(Colorectal Neoplasms) :
IL-12 may
regulate VEGF in the patients diagnosed with colorectal cancer
Kang et al., Leukemia & lymphoma 2006
(Leukemia) :
Inhibition of cellular
VEGF levels
increased interleukin (IL)-12 production and the allostimulatory capacity of leukemic DCs
Block et al., Clin Cancer Res 2011
(Mammary Neoplasms, Experimental...) :
Human but not mouse APCs upregulate VEGFR2 and downregulate
interleukin (IL)-12ß in
response to
VEGF
Ferrante et al., Inflammation 2013
:
Adenosine signaling suppresses the TLR dependent expression of TNF-a,
IL-12 , IFN-?, and several other inflammatory cytokines by macrophages and
induces the expression of vascular endothelial growth factor (
VEGF ) and IL-10
Burnham et al., Am J Physiol Lung Cell Mol Physiol 2013
(Alcoholism) :
Cigarette smoking duration was associated with higher IL-1ß ( P = 0.0009 ) but lower VEGF ( P = 0.0007 ) ; cigarette smoking intensity was characterized by higher IL-1ß and lower
VEGF and
diminished IL-12 ( P = 0.0004 )
Matsumoto et al., Nephron 1998
(Glomerulonephritis, IGA...) :
We, therefore, investigated the
effects of recombinant human
IL-12 on the release of
VPF by peripheral blood mononuclear cells ( PBMC ) from LN patients ... Recombinant human
IL-12 was found to
enhance VPF release in a dose dependent manner
Dias et al., Int J Cancer 1998
(Mammary Neoplasms, Experimental...) :
IL-12 regulates
VEGF and MMPs in a murine breast cancer model