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APOB — NOX1

Text-mined interactions from Literome

Pritchard et al., Free Radic Biol Med 2002 : n-LDL increased NOx by more than 4-fold while having little effect on A23187 stimulated nitrite production
Toma et al., Biochem Biophys Res Commun 2009 (Hyperglycemia...) : The addition of 25mM glucose in the culture medium enhanced the effect of AGE-LDL , but also of nLDL, on RAGE, p22(phox), NOX4 , p67(phox), and MCP-1 gene expression
Zhao et al., Free radical research 2011 : The present study demonstrated that oxidized LDL ( oLDL ) increased the generation of superoxide and hydrogen peroxide ( H ( 2 ) O ( 2 ) ), the abundances of NADPH oxidase (NOX)4, NOX2 , p22-phox and lectin-like oLDL receptor-1 ( LOX-1 ) in wild-type or heat shock factor-1 (HSF1)-deficient mouse embryo fibroblasts (MEF)
Shen et al., Cardiovasc Hematol Disord Drug Targets 2012 : Glycated and oxidized LDL increase the expression of NOX and ROS production in EC
Xie et al., International journal of molecular sciences 2012 : Impact of Cyanidin-3-Glucoside on Glycated LDL Induced NADPH Oxidase Activation, Mitochondrial Dysfunction and Cell Viability in Cultured Vascular Endothelial Cells
Jessup et al., Atherosclerosis 1993 : The NADPH oxidase inhibitor, diphenylene iodonium, did inhibit macrophage mediated modification of LDL , but its effects do not appear to involve superoxide generation
Aviram et al., Metabolism 1996 (Granulomatous Disease, Chronic) : Under these conditions, the cytosolic protein components of the NADPH oxidase complex, P-47 and P-67, translocated to the plasma membrane, indicating LDL mediated activation of the NADPH oxidase complex ... We thus conclude that LDL induced NADPH oxidase activation ( under oxidative stress ) is required for macrophage mediated oxidation of LDL, whereas activation of 15-lipoxygenase may not be sufficient for LDL oxidation under these conditions